RE: IgA nephropathy recurrence post transplant 4 hours ago

UTO may cause proteinuria by causing tubular injury with reduce PCT reabsorption of proteins and possible increase glomerular capillary for HMWT pr...

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RE: IgA nephropathy recurrence post transplant 11 hours ago

Will be interesting to see if UAlb/Cr and UPr/Cr decrease/normalize on serial measurements with no further specific intervention. If this occurs, i...

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RE: Peritoneal Dialysis - Improvements for patients wellbeing - Request for comments 11 hours ago

The idea one puts fluid with 15 x higher than serum concentration of sugar into sick person's (commonly with diabetic complications) abdomen for fe...

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RE: IgA nephropathy recurrence post transplant 12 hours ago

This could be donor derived IgA deposition disease which has a very favorable prognosis without treatment. . ------------------------------ Rich...

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RE: IgA nephropathy recurrence post transplant 12 hours ago

It depends on the clinical features , and concomitant C3 and C4 deposition. ------------------------------ Richard Glassock MD, FASN Laguna...

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RE: IgA Nephropathy Case: Recurrent Cellulitis & Treatment Considerations 12 hours ago

Rosacea has a well known association with hypothyroidism (autoimmune ) and gluten sensitive enteropathy (Celiac Disease ) which in turn is associat...

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RE: IgA nephropathy recurrence post transplant 13 hours ago

@Daniel Guevara-Pineda: "EM there are patent capillary loops , there are no sub epithelial deposits no intramembranous deposits either there is mil...

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IgA Nephropathy Case: Recurrent Cellulitis & Treatment Considerations 13 hours ago

IgA Nephropathy Questions Patient: 50s-year-old female, recently diagnosed with IgA nephropathy Comorbidities: Morbid obesity and hypertension I...

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RE: 36g proteinuria - anti nephrin antibody testing sites in USA 17 hours ago

Suspected could not confirm ------------------------------ Partha Raguram MBBS, MD, FASN MD MRCPI FASN Oregon Kidney hypertension Tigard OR (253...

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RE: 36g proteinuria - anti nephrin antibody testing sites in USA 17 hours ago

Just started steroids.. monitoring UP/Cr ratio and albumin..DM on insulin ------------------------------ Partha Raguram MBBS, MD, FASN MD MRCPI ...

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RE: Hyperphosphatemia and horse milk 17 hours ago

Dr Glassock, thanks for the comment, I knew about goat's milk, but not horse. Interesting if it does interfere. ------------------------------ St...

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RE: 36g proteinuria - anti nephrin antibody testing sites in USA 17 hours ago

How long he was on high dose steroids? Any decrement in UPCR or increment of serum albumin? --------------------------------- Hayder Aledan MD, FA...

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RE: IgA nephropathy recurrence post transplant 17 hours ago

We proceed with stenting and dilations procedures by interventional radiology before considering ureter reimplantarion --------------------------...

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RE: IgA nephropathy recurrence post transplant 18 hours ago

I have similar case few months ago that was treated with ureter reimplantation which results in return of RFT to baseline levels. Is it premature t...

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RE: Hyperphosphatemia and horse milk 18 hours ago

According to available literature mares milk is lower in Phosphorous than cows milk but goats milk is higher in Phosphorous content than Cows milk....

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RE: Hyperphosphatemia and horse milk 18 hours ago

Please see following reference courtesy of Google AI. Table 4 in the article lists calcium and pho content in mate vs cow vs human milk. https://p...

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RE: IgA nephropathy recurrence post transplant 18 hours ago

Agree with unlikely a rejection give negative findings on biopsy negative dsa and donor cell free dna of 0.3% he did not have post obstructive di...

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RE: Seeking Expert Opinion on HIV-Associated Immune Complex Glomerulonephritis (HIVICK) Treatment 18 hours ago

Dr. Venkat- agreed. This is a desperate situation. How would you manage this patent? . Immunizations pre-C inhibition may be ineffective in this ca...

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RE: IgA nephropathy recurrence post transplant 18 hours ago

Encouraged by prompt decrease of SCr to 2.4 mg within a day after PCNU and now to 2.2 CMO Gmg. This trend makes rejection less likely. Since obstru...

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RE: Seeking Expert Opinion on HIV-Associated Immune Complex Glomerulonephritis (HIVICK) Treatment 19 hours ago

One concern with complement inhibition will be increased susceptibility to infection in this HAART-naive HIV patient with very low CD4 count. --...

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RE: IgA nephropathy recurrence post transplant 19 hours ago

Thanks- would add DD-cfDNA and depending on results consider molecular biopsy if Creat remains elevated. ------------------------------ [Mark] [...

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Hyperphosphatemia and horse milk 19 hours ago

I had an interesting encounter with a CAPD pt of mine. He is 45 and been on CAPD for about 6 months and has been doing very well, with serum phosph...

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RE: Electrolyte Case 19 hours ago

@Andres Valdivieso agree with Dr. Venkat that the cause is hypothalamic nephropathy whether microcytic formation or tubulointerstitial fibrosis (CI...

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RE: Idiopathic asymptomatic hypercalciuria 19 hours ago

The role of heavy metals has been the topic of a moderate number of studies in the stone field. Some heavy metals (eg cadmium) are clearly known to...

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RE: Seeking Expert Opinion on HIV-Associated Immune Complex Glomerulonephritis (HIVICK) Treatment 20 hours ago

This case certainly fits the description of nonLulus full house Nephropathy dud to HIVICK . Therapy with HAART is indicated , but a role for immuno...

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RE: Electrolyte Case 20 hours ago

@Tunde Tijani Calculated UOsm = 2 [Na + K] + BUN/2.8 + glucose /18 So urine K is add to urine Na and both doubled -------------------------------...

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RE: IgA nephropathy recurrence post transplant 20 hours ago

Yes we have and this is mainly albuminuria > 60% ------------------------------ Daniel Guevara-Pineda MD West Hartford CT ----------------------...

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RE: IgA nephropathy recurrence post transplant 21 hours ago

Given less than expected recovery from post obstructive nephrostomy and potentially unexplained proteinuria - have you not checked for non albumin ...

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RE: Electrolyte Case 21 hours ago

Does anyone have and can share the classic paper (on JCI) on this subject published by Dr. M. Halperin et al? I lost mine and cannot download a cop...

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RE: Peritoneal Dialysis - Improvements for patients wellbeing - Request for comments 23 hours ago

Great question! I say there may be some glucose, and icodextran or analogue. But i am planning mostly build it on Na and Cl If we just kee...

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RE: Electrolyte Case 23 hours ago

Absence of cysts does not rule out chronic hypokalemic nephropathy, but their presence makes it more likely than diabetic nephropathy. Agree with y...

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Seeking Expert Opinion on HIV-Associated Immune Complex Glomerulonephritis (HIVICK) Treatment 1 day ago

Dear colleagues, I have a 43-year-old French male patient presenting with rapidly progressive glomerulonephritis (RPGN), likely due to HIV-associa...

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RE: Peritoneal Dialysis - Improvements for patients wellbeing - Request for comments 1 day ago

Without glucose or Icodextrin how will you assure adequate volume control? ------------------------------ Richard Glassock MD, FASN Laguna Woods ...

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RE: Electrolyte Case 1 day ago

Thanks Dr Venkat for your response Actually her serum potassium levels very frequently have been < 3,5 me/l However she does not have macroscóp...

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RE: Peritoneal Dialysis - Improvements for patients wellbeing - Request for comments 1 day ago

Hi dr Glassock, thank you for kind words, not yet, I do not have funding, I am planning to search for funding grants and investors, first collectin...

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RE: Peritoneal Dialysis - Improvements for patients wellbeing - Request for comments 1 day ago

Hi, dr Rodby, So absolutely agree, the CFPD (continuous flow peritoneal dialysis) has many already known benefits - and we know this for decades (...

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RE: Electrolyte Case 1 day ago

@Andres Valdvieso: Regarding your patient with Bartter syndrome, how good has the long-term correction of hypokalemia been? Any cysts on renal imag...

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RE: Peritoneal Dialysis - Improvements for patients wellbeing - Request for comments 1 day ago

Have you applied to FDA for an investigational device approval so you can conduct comparison evaluation of your novel device vs standard PD therapy...

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RE: Electrolyte Case 1 day ago

I would like to ask your advice I have been in charge for thirty years , of a 44 year old lady with type III Bartter's Syndrome. Her BP is 90/60...

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RE: 36g proteinuria - anti nephrin antibody testing sites in USA 1 day ago

With 26 grams U protein/24 hrs and serum alb of 0.8, and assuming just 20% of U protein was albumin it suggests he is excreting around 10% of circu...

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RE: Peritoneal Dialysis - Improvements for patients wellbeing - Request for comments 1 day ago

How is this different? https://pmc.ncbi.nlm.nih.gov/articles/PMC9796292/ ------------------------------ Roger Rodby MD, FASN Professor of Medic...

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RE: Electrolyte Case 1 day ago

Why is U Na double and not urine K? ------------------------------ John Mellas MD Nephrology and Hypertension Specialists St Louis MO 3145372356 ...

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RE: Idiopathic asymptomatic hypercalciuria 1 day ago

I think I agree with Dr. Kiljanek , but I have no idea how cost efffective the approach of 'routine screening " for occult heavy metal intoxication...

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RE: Seronegative AntiGM disease! 1 day ago

The possibilities of a "prozone" phenomenon or an "immunologic sink" hypothesis are very intriguing. In my experience both a rather unlikely. A pro...

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RE: Idiopathic asymptomatic hypercalciuria 1 day ago

Why not? If positive: Fully treatable/reversible cause. Testing is accessible, non invasive and cheap. If not tested: can have devastating...

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RE: Electrolyte Case 1 day ago

Calculated Uosm: 2 x (urine Na) + urine K + (urine urea nitrogen/2.8) + (urine glucose/18). Note that the K+ is not doubled.. also note that the...

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RE: Idiopathic asymptomatic hypercalciuria 1 day ago

Unless there is something suggesting the possibility in the history, I do not routinely check, though it is a possibility -----------------------...

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RE: IgA nephropathy recurrence post transplant 1 day ago

With in 48 hrs the patient received PCNU the following day cr decreased from 3.1 to 2.4 and now is 2.2 . There was a slow decline of renal function...

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RE: IgA nephropathy recurrence post transplant 1 day ago

How soon after the SCr rose to 3.1 mg/dL was nephrostomy placed? Obviously, longer this interval more likely is incomplete kidney function recovery...

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RE: IgA nephropathy recurrence post transplant 1 day ago

My bad. Thank you for the clarification. I am sure that the ULD (NKR swap) had no evidence of renal disease when he/she was accepted but a clinical...

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